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New Extensively-Drug Resistant Organism (XDRO) Registry Reporting and Querying Requirements​

77 Illinois Administrative Code, Part 690 Control of Notifiable Diseases and Conditions Code, was amended effective February 2024. The purpose of this memo is to notify mandated reporters and health care providers of changes related to the control of multi-drug resistant organisms and Extensively Drug-Resistant Organism (XDRO) Registry reporting and querying.

  • ​A new section, Section 690.540, was created for the control of Multi-drug Resistant Organisms of Epidemiologic Importance. At this time, carbapenem-resistant Enterobacterales (CRE) and Candida auris only are included under this section and are reportable to the XDRO registry. ESBLs are not included in this reporting requirement.

  • Direct, manual reporting of C. auris to the XDRO registry by mandated reporters will open and be required as of July 1, 2024. Reporters must also report epidemiologic investigation data for new cases to the Illinois-National Electronic Disease Surveillance System (I-NEDSS).
    • IDPH will work with laboratories to establish electronic laboratory reporting to I-NEDSS, and a dataflow to the XDRO registry to eventually replace manual data entry.

  • ​Under Section 690.1510​, new entities required to report to the XDRO registry include dialysis centers, specialized mental health rehabilitation facilities, and other high-risk health care facilities serving high-risk populations. These entities may also have their laboratories report on their behalf.

  • The following health care facilities are now required to query new admissions or implement automated alerts from the XDRO registry: Hospitals, long-term acute care hospitals, skilled nursing and intermediate care facilities, and dialysis centers.

Facilities that do not currently have IDPH Web Portal and XDRO registry access must register here: https://portalhome.dph.illinois.gov/. Registration instructions and a quick training video are also available on the XDRO registry website.

Please contact DPH.XDROregistry@illinois.gov with questions.
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